GT 949

CAS No. 460330-27-2

GT 949 ( —— )

Catalog No. M26706 CAS No. 460330-27-2

GT 949 is a selective excitatory positive allosteric modulator of amino acid transporter-2 (EAAT2) (EC50: 0.26 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 58 Get Quote
10MG 102 Get Quote
25MG 205 Get Quote
50MG 372 Get Quote
100MG 556 Get Quote
500MG 1197 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    GT 949
  • Note
    Research use only, not for human use.
  • Brief Description
    GT 949 is a selective excitatory positive allosteric modulator of amino acid transporter-2 (EAAT2) (EC50: 0.26 nM).
  • Description
    GT 949 is a selective excitatory positive allosteric modulator of amino acid transporter-2 (EAAT2) (EC50: 0.26 nM).(In Vitro):GT 949 displays selectivity to EAAT2 and has no effect on glutamate activity mediated by EAAT1 or EAAT3. GT 949 improves glutamate transport (EC50 = 0.26 nM) and increases glutamate transport in a non-competitive manner with an increase in Vmax of about 47% in EAAT2-transfected cells.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    5-HT; Dopamine
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    460330-27-2
  • Formula Weight
    527.7
  • Molecular Formula
    C30H37N7O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc1ccc2[nH]c(=O)c(cc2c1)C(N1CCN(CC1)C1CCCCC1)c1nnnn1CCc1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shan-Meng Lin, et al. Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design. J Med Chem. 2020 Mar 26;63(6):3131-3141.
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